Neuromodulation April 11, 2026
Neuromodulation for Migraine Prophylaxis: Network Meta-Analysis of 40 RCTs (2026)
Ke et al. (2026): tES is most effective for reducing migraine days, tONS for improving treatment response rates.
Comparing neuromodulation techniques for migraine prophylaxis: 40 RCTs, 4,341 patients.
Findings
tES (SUCRA 82%) most effective for reducing migraine days, tONS (SUCRA 90%) highest response rate, PMES (SUCRA 96%) best pain reduction.
Ref: Ke D, et al. BMC Complement Med Ther. 2026;26:74.